BETUAS

Betaxolol HCL

Betaxolol hydrochloride

Eye-drops 0,5%; in bottle-droppers 5ml

Formula: 1ml contains:

• Active substance: Betaxolol hydrochloride 5,6mg (5,0 mg pure Betaxolol equivalent)
• Conserving agent: benzalkonium chloride 0,01%

Non-active substances: sodium chloride, sodium edetate, hydrochloric acid/ sodium hydroxide, purified water.

Pharmacological group: Beta-adrenergic blocking agents

Pharmacological action: Antiglaucomic. Blocks beta 1- adrenoreceptors. Decreases production of intraocular fluid, lowers internal eye pressure (high and normal).

Indications: Chronical open-angle glaucoma, eye hypertension (as monotherapy or in combination with other preparations).

Contraindications: Hypersensitivity to any component of the preparation, sinus bradycardia, AV block of II–III degree, cardiogenic shock, severe heart failure in history.

Application during pregnancy and lactation period: Application is possible only if desirable effect of the therapy exceeds its potential risk for the fetus. During lactation period should be used with care.

Side effects: Local: blear-eyedness (directly after instillation), cornea hyposensitization,

erythema, itching, soreness, eye dryness, photophobia, anisocoria.

Systemic effects:

Nervous system and sensory organs: dizziness, drowsiness, insomnia, depression, intensification of myasthenia symptoms.

Cardio-vascular system and blood (hematogenesis, hemostasis): rarely — bradycardia, heart block.

Respiratory system: dyspnea (in isolated cases).

Interaction: During simultaneous use of beta-adrenergic blocking agents per os it is possible to have mutual intensification of local (lowering of internal eye pressure) and systemic (hypotension, bradycardia) effects; on the background of sympathomimetics (reserpine) the increase of hypotension and bradycardia is possible.

Application and dosage: Conjunctival, 1–2 drops 2 times daily in the affected eye (controlling internal eye pressure).

Precautionary measures: With care should be prescribed to patients with diabetes, thyrotoxicosis, pheochromocytoma, Raynaud's syndrome, myasthenia, on the background of adrenergic psychotropics.

Use should be gradually discontinued 48 hours prior to surgical interference with general anesthesia.

Package: plastic bottles 5ml

Expiry period: Do not take the preparation after the expiry date printed on the package. After unsealing the bottle, expiry date of the solution- 30 days.

Storage conditions: B list. Under indoor temperature, in the dark place.

Keep out of reach of children.

Conditions of delivery at chemistry stores:

Delivered according to prescription.